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阻害剤 血管新生 アポトーシス オートファジー 細胞周期・チェックポイント クロマチン・エピジェネティック 細胞骨格シグナル DNA損傷・DNA修復 内分泌・ホルモン GPCR/Gタンパク質 免疫・炎症 JAK・STATシグナル MAPK
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シグナル伝達経路 血管新生 アポトーシス オートファジー 細胞周期・チェックポイント クロマチン・エピジェネティック 細胞骨格シグナル
DNA損傷・DNA修復 内分泌・ホルモン GPCR/Gタンパク質 免疫・炎症 JAK・STATシグナル MAPK 膜輸送体・イオンチャネル
代謝 微生物学・ウィルス学 神経科学 NF-Κb 酸化還元 PI3K/Akt/mTORシグナル プロテアーゼ・プロテアソーム
幹細胞 チロシンキナーゼ・アダプター ユビキチン その他 PROTAC
生物活性化合物ライブラリー ゼネラルバイオウアクティヴライブラリー 承認/再開発 医薬品ライブラリー 疾患別 化合物ライブラリー 標的/経路別 化合物ライブラリー 特徴的な生物活性化合物ライブラリー
天然化合物ライブラリー HTS用天然物ライブラリー 分野別 天然化合物ライブラリー 天然物誘導体ライブラリー CADD用天然物ライブラリー
ドラッグライク 化合物ライブラリー ドラッグライクライブラリー
フラグメントライブラリー ゼネラルフラグメントライブラリー 特徴的なフラグメントライブラリー カスタム化合物ライブラリー
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

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Search Results for " embryonic stem cells "

ターゲット

Casein Kinase

24

阻害剤

1

天然化合物

20

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T8987 Epiblastin A Casein Kinase
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).
T16695 Pyrintegrin Integrin
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...
T2161 Cardiogenol C Wnt/beta-catenin
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
T21981 Phthalazinone pyrazole Aurora Kinase
Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.
T3221 Oct3/4-inducer-1 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile Others , OCT
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.
T8005 Cardiogenol C hydrochloride Cardiogenol C HCl,Cardiogenol C Wnt/beta-catenin
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
T3162 IDE1 Others
IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM...
T11469 GSK-3484862 DNA Methyltransferase
GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.
T2019 OAC2 OCT
OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibrobl...
T28866 Stemazole Apoptosis
Stemazole is a novel small molecule human stem/progenitor cell proliferation activator that promotes the survival of human embryonic stem cells and maintains stemness, and promotes the survival of oligodendrocyte precurs...
T60143 MitoBloCK-6 Apoptosis
MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC 50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 with IC 50 of 1.4 μM. MitoBloCK-6 can induce apoptosis via cytochrome c release in human embryo...
T2310 CHIR-99021 Laduviglusib,CT99021,CHIR-99021 GSK-3 , Wnt/beta-catenin , Autophagy
CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in...
T2301 SB 202190 FHPI,SB202190 Apoptosis , p38 MAPK , Autophagy
SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably. SB 202190 has antitumor activity and also induces the differentiation of human embryonic stem cells i...
T3637 Pifithrin-β hydrobromide Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide) Ferroptosis , p53
Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorder...
T2310L CHIR-99021 HCl CT99021 HCl,Laduviglusib HCl GSK-3
CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3α/β, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivit...
T70520 TWS-119
TWS-119 is an inhibitor of glycogen synthase kinase-3β (GSK-3β) that induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs).
T35549 Elsinochrome A
Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus ...
T69743 MEDS433
MEDS433 is a dihydroorotate dehydrogenase inhibitor (IC50 1.2 nM). MEDS433 inhibited the in vitro replication of hCoV-OC43 and hCoV-229E, as well as of SARS-CoV-2, at low nanomolar range. Notably, the anti-SARS-CoV-2 act...
T35561 MS351
MS351 is an antagonist of chromobox 7 (CBX7) that acts by binding the CBX7 chromodomain. It enhances the binding of long noncoding RNA to the CBX7 chromodomain when used at 25 μM. MS351 induces transcriptional derepressi...
T35553 Ganglioside GQ1b Mixture (sodium salt)
Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO hu...
T35592 SB 202190 hydrochloride
SB 202190 hydrochloride is a selective and cell-permeable p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM). SB 202190 hydrochloride has anti-tumor activity and can also induce the differentiation of human...
T76052 ELA-32(human) TFA
ELA-32(human) TFA is a potent apelin receptor agonist with high affinity, demonstrating an IC50 of 0.27 nM and a Kd of 0.51 nM. This compound does not bind to GPR15 or GPR25. It activates the PI3K/AKT signaling pathway, ...
T76068 Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA
Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA (Cyclo RGDfC) TFA, a cyclic RGD peptide, displays a high affinity for αvβ3 integrin, effectively disrupting cell-integrin interactions. It suppresses pluripotent marker expression in embr...
T35922 NAADP (sodium salt)
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a secondary messenger that induces calcium mobilization. It induces calcium release from endosomes and lysosomes via two-pore channel 2 (TPC2) and TPC1, which then...
カタログ番号 製品名 別名 ターゲット
T75661 Thymopentin acetate
Thymopentin acetate, primarily secreted by the epithelial cells of the thymic cortex and medulla, serves as an effective immunomodulatory agent. It possesses a short plasma half-life of 30 seconds and significantly enhan...

天然物製品

Thymopentin acetate
T75661
Synonym:
Target:

Recombinant Proteins

Species：
Human (12)
Mouse (8)
Expression System：
E. coli (11)
HEK293 Cells (6)
Baculovirus Insect Cells (3)
Tag：
C-His (3)
N-6xHis (3)
C-hFc (2)
N-10xHis, C-Myc (2)
N-GST (2)
Tag Free (2)
C-6xHis (1)
His, GST (1)
N-10xHis (1)
N-His (1)
カタログ番号 製品名 Species Expression System
TMPY-05004 FGF-4 Protein, Human, Recombinant Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept...
TMPJ-00879 HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His) Human E. coli
Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators...
TMPK-01186 B7-H5/Gi24/VISTA Protein, Human, Recombinant (His) Human HEK293 Cells
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-...
TMPK-00868 Notch 4 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression ...
TMPH-02579 CHRDL1 Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus Insect Cells
Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal different...
TMPJ-00835 FGF-4 Protein, Mouse, Recombinant Mouse E. coli
Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that ...
TMPK-01185 B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc) Human HEK293 Cells
B7-H5, also known as VISTA , B7H5, Dies1, SISP1 and C10orf54, is a 55-65 kDa member of the Ig superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. B7-...
TMPH-01720 C-Myc Protein, Human, Recombinant (His) Human E. coli
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPH-01961 Wnt3a Protein, Human, Recombinant (His) Human E. coli
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal ...
TMPH-01721 C-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated Human E. coli
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPH-02859 Wnt3a Protein, Mouse, Recombinant (His) Mouse E. coli
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal ...
TMPH-02791 C-Myc Protein, Mouse, Recombinant (GST) Mouse E. coli
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPJ-00200 EpCAM/TROP1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with...
TMPY-01345 ACBD6 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Human acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus. In mammals, there are six members ...
TMPY-02921 CDK2AP2 Protein, Human, Recombinant (His) Human E. coli
CDK2AP2 belongs to the CDK2AP family. Members of this family of proteins are cell-growth suppressors, associating with and influencing the biological activities of important cell cycle regulators in the S phase including...
TMPY-02950 WWP2 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
WWP2 contains 1 C2 domain, 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain and 4 WW domains. It is an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thio...
TMPH-01288 Elongin-B Protein, Human, Recombinant (GST) Human E. coli
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its...
TMPH-01642 MELK Protein, Human, Recombinant (His & Myc) Human E. coli
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25...
TMPY-04534 GDF-8 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
GDF-8 / Myostatin / MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to pro...
FGF-4 Protein, Human, Recombinant
TMPY-05004
Species: Human
Expression System: E. coli
Noggin/NOG Protein, Mouse, Recombinant (His)
TMPJ-01065
Species: Mouse
Expression System: HEK293 Cells
HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)
TMPJ-00879
Species: Human
Expression System: E. coli
B7-H5/Gi24/VISTA Protein, Human, Recombinant (His)
TMPK-01186
Species: Human
Expression System: HEK293 Cells
Notch 4 Protein, Mouse, Recombinant (His)
TMPK-00868
Species: Mouse
Expression System: HEK293 Cells
CHRDL1 Protein, Mouse, Recombinant (His & Myc)
TMPH-02579
Species: Mouse
Expression System: Baculovirus Insect Cells
FGF-4 Protein, Mouse, Recombinant
TMPJ-00835
Species: Mouse
Expression System: E. coli
B7-H5/Gi24/VISTA Protein, Human, Recombinant (hFc)
TMPK-01185
Species: Human
Expression System: HEK293 Cells
c-Myc Protein, Human, Recombinant (His)
TMPH-01720
Species: Human
Expression System: E. coli
Wnt3a Protein, Human, Recombinant (His)
TMPH-01961
Species: Human
Expression System: E. coli
c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated
TMPH-01721
Species: Human
Expression System: E. coli
Wnt3a Protein, Mouse, Recombinant (His)
TMPH-02859
Species: Mouse
Expression System: E. coli
c-Myc Protein, Mouse, Recombinant (GST)
TMPH-02791
Species: Mouse
Expression System: E. coli
EpCAM/TROP1 Protein, Mouse, Recombinant (hFc)
TMPJ-00200
Species: Mouse
Expression System: HEK293 Cells
ACBD6 Protein, Human, Recombinant (His)
TMPY-01345
Species: Human
Expression System: Baculovirus Insect Cells
CDK2AP2 Protein, Human, Recombinant (His)
TMPY-02921
Species: Human
Expression System: E. coli
WWP2 Protein, Human, Recombinant (His & GST)
TMPY-02950
Species: Human
Expression System: Baculovirus Insect Cells
Elongin-B Protein, Human, Recombinant (GST)
TMPH-01288
Species: Human
Expression System: E. coli
MELK Protein, Human, Recombinant (His & Myc)
TMPH-01642
Species: Human
Expression System: E. coli
GDF-8 Protein, Mouse, Recombinant (hFc)
TMPY-04534
Species: Mouse
Expression System: HEK293 Cells
カタログ番号 製品名
L8000 Stem Cell Differentiation Compound Library

1197 compounds
A unique collection of 1197 stem cell differentiation signaling targeted compounds for high throughput and high content screening;

ライブラリー

Stem Cell Differentiation Compound Library
L8000
Compounds: 1197
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